A protocol for the application of the Interpersonal Therapy (IT) to relatives of eating disordered (ED) patients is presented. The aim of the psychotherapy program was to improve the relationships between the ED patients and their parents in order to favor the cognitivebehavioral treatment of the ED. The IP was applied to 27 families in 20 structured sessions following a group format and combining IP strategies with cognitive-behavioral techniques. The IP efficacy has been assessed using a semi-structured interview (pre- vs. post-treatment, at 12- months follow-up). The results show significant positive changes in the relationships pattern between parents and patients.